动更年迈的可能保护大脑痴呆

Moving more in old age may protect brain from dementia


痴呆 信用:CC0公共领域

老年人比移动均匀,无论在形式的日常锻炼,或只是日常膂力活动如做家务,可以坚持更多的记忆和考虑能力的人比活性低于均匀水平,即便他们有脑部病变或生物标志物与老年痴呆症,依据一项研讨由Rush大学医学中心宣布在2019年1月16日,在线出版的 i 神经病学 /i 、医学杂志的美国神经病学学会。

研讨人员发现,运动可以协助坚持思维和记忆能力有AD大脑中存在的标志提供认知贮藏。

研讨比较了认知测试成果和活动数据,454的老年人

该研讨评价了454191有;263没有。所有的参加者进行了体检和思维和记忆测试,每一年为20年。

与会者同意捐赠大脑的研讨对他们的死亡。在死亡的均匀年纪为91岁。

在前两年均匀死亡,来自Rush阿尔茨海默病中心的研讨人员给每一个参加者一个监控活动称为加速度计。The wrist-worn device monitored physical activity around the clock, including everything from small movements such as walking around the house to more vigorous activity like exercise routines.

Researchers collected and evaluated seven days of movement data for each participant and calculated an average daily activity score. The results were measured in counts per day, with an overall average of 160,000 counts per day.

People without dementia had an average of 180,000 counts per day, and people with dementia had an average of 130,000 counts per day.

Researchers found that higher levels of daily movement were linked to better thinking and memory skills. The study also found that people who had better motor skills—skills that help with movement and coordination—also had better thinking and memory skills.

Little differences in activity correlated with big differences in dementia rates

For every increase in physical activity by one standard deviation, participants were 31 percent less likely to develop dementia. For every increase in motor ability by one standard deviation, participants were 55 percent less likely to develop dementia.

Buchman说,分析标明,身体活动和运动能力占人的记忆思维测试得分之间的差异百分之八。

人身后,研讨人员查看了他们的捐赠,寻找病变和痴呆和阿尔茨海默病的生物标志物。

活动和考试成果之间的关系是一致的乃至当研讨人员调整了参加者的程度。他们还发现,在那些患有痴呆症的关系的人和没有痴呆是一致的。

较高的膂力活动水平和更好的思维和记忆能力之间的联络是对阿尔茨海默病及相关疾病的生物标志物的存在无关。

锻炼可以保护大脑,但需要更多的研讨

“锻炼是改善威尼斯人备用网站地址的一种廉价的方式,和我们的研讨标明,它可能有脑保护作用,”Buchman说。”但需要留意的是,我们的研讨没有说明原因和效果的重要。